What Is BIST® (Beads array In Single Tip)?

How It Works

BIST® (Beads array In Single Tip) is a multiplex detection tool developed for automated simultaneous multi-item measurements.

1mm diameter beads coated with a single immobilized antibody, antigen or DNA fragment are lined up inside the BIST® tip. Sample is automatically pipetted through the tip, binding target substances to the beads. After an enzymatic reaction, signals can be detected and measured simultaneously from up to 20 different bead-targets.

PSS will support your application development using BIST®, including reagent prepacking, reaction process and detection automation.

Multiplex Assays Suitable for BIST® Analysis

Body testing (Obesity factors)
Allergic reaction tests
Cedar, cypress, ragweed, HD (tick, cat, dog etc.)
Cancer markers
AFP (hepatoma), PSA (prostatic cancer), p53 antibody
Cancer-related tests
HLA Typing, sugar chain detection
Cardiac disease marker
Myoglobin, troponin, PCT
Clinical testing items
TSH, Free T3, Free T4, AFP, albumin
Infant mass screening
TSH, 17-OHP, Free T4
Dried blood spot
IK28, SYP2C19, EGFR (Iressa target agent)
Immunodeficiency disease
CD3 (T lymphocytes), CD19 (B lymphocytes), CD45 (leukocyte)
Food allergens
Wheat, buckwheat, peanuts, eggs, milk, shrimp, crab
Genetically modified food (GMO) protein
Herbicide resistant enzyme PAT, CP4-EPSPS
Food (corn, soy beans)
Genetically modified food (GMO) genes
Specific gene detection
Food (corn, soy beans)
Crop production location identification, variety identification
Tuna variety identification, cashmere identification
Meat, hair, etc.
Food poisoning
Salmonella (bacteria), Staphylococcus aureus (bacteria, toxins: enterotoxins), Vibrio parahaemolyticus (bacteria), Bacillus cereus (bacteria, toxins), E. coli (bacteria, toxins)
Stool, food
Legal communicable disease
Cholera, dysentery, typhoid
Stool, food
Diarrheal viruses
Norovirus, rotavirus, adenovirus
Stool, food
Enterohaemorrhagic E. coli
O157, O26
Stool, food
Infectious disease
Mumps, EV virus
Water examination

Automation for BIST®



LuBEA® is a compact fully automated reaction measurement device for simultaneous multiple analyte detection tool "BIST®". Automated protocols utilize prepacked reagents for the reaction, washing and detection processes.



LuBEA® VIII is the high throughput version of LuBEA®. Using the new R x F Scanner, up to 8 BIST® tubes can be processed at the same time, for higher throughput. It is currently under development.

Meeting the Changing Demands of Specialized Fields

Simplifying the Science of Discovery

PSS is committed to the rapid development of products in various fields such as infectious disease, oncology, genetics, human identification, animals, and plants in order to contribute to the world’s ongoing health needs.

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